What is HydroCell™ technology?
Your skin naturally produces hyaluronic acid – a molecule that plays an important role in keeping your skin hydrated. E45 HydroCell™ technology has been expertly formulated to activate this natural process, boosting your skin’s own production of hyaluronic acid by up to 211%² to deliver three times more hydration than hyaluronic acid alone³. HydroCell™ technology works at a cellular level within the skin’s surface layers, helping the skin to hydrate itself from within. Powered by a marine-derived active sourced from red algae, HydroCell™ technology combines the proven skincare benefits of marine algae with advanced hydration science.

How does HydroCell™ technology work?

1. Activates the skin’s natural hyaluronic acid production
Hyaluronic acid is one of the skin’s most important natural moisturisers. It binds water within skin cells and is what gives the skin its plump, hydrated look. Your skin produces hyaluronic acid via an enzyme called Hyaluronan Synthase 3 (HAS3). HydroCell™ technology stimulates HAS3 directly, helping the skin to generate up to 211% more of its own hyaluronic acid.²
2. Hydrates up to 10 layers deep
Because HydroCell™ technology works with your skin’s natural biology, hydration isn’t limited to the surface.
Instead, HydroCell™ technology supports hydration up to 10 layers deep within the stratum corneum,¹ delivering up to 3× more hydration than hyaluronic acid alone.³

3. Strengthens the skin barrier with ceramides
In skincare, ceramides are the lipids that act as a protective cement between the skin cells, holding the barrier together. HydroCell™ technology stimulates ceramide production,² increasing synthesis by up to 51% in the stratum corneum and up to 56% in the upper epidermis.²
What is the skin barrier, and how does HydroCell™ technology strengthen it?
The skin barrier is the outermost layer of the skin, responsible for keeping moisture in and environmental stressors out. When it’s compromised, skin loses moisture more easily, feels more reactive, and can look dull. Knowing how to strengthen the skin barrier is one of the most important steps in any long-term skincare routine.

That’s where ceramides come in. They’re the lipid molecules that hold the barrier together, forming a protective structure between skin cells that reduces water loss. When ceramide levels drop, the barrier weakens and moisture retention falls. E45 HydroCell™ technology directly stimulates ceramide production – up to 51% in the stratum corneum and up to 56% in the upper epidermis.²

Where does HydroCell™ technology come from?
E45 HydroCell™ technology is powered by a marine-derived active ingredient from red algae, sourced in mineral-rich waters off the Scandinavian coast – where marine plants have evolved to thrive in tough conditions. A marine-derived ingredient like this works in harmony with the skin’s own biological processes, rather than acting on it from the outside.

It’s one of the clearest examples of marine algae skincare benefits put to work: not introducing a substitute for the skin’s natural hydration, but supporting what the skin already does.
Explore the E45 HydroCell™ technology range
E45 HydroCell™ technology powers all three products in the range. Each pairs HydroCell™ technology with a targeted active – so whether you’re looking for a BHA body lotion for texture, a brightening body lotion for radiance, or a firming body cream for elasticity, there’s a HydroCell™ formula for you.
Frequently asked questions about HydroCell™ technology
What does ‘clinically proven’ mean for HydroCell™ technology?
HydroCell™ technology efficacy is supported by two test types. In vivo testing showed 3× more hydration than hyaluronic acid alone.³ Ex vivo testing showed up to 211% more hyaluronic acid production in just 9 days, ceramide increases of up to 51–56%, and barrier-strengthening effects lasting up to 100 hours after one application.²
How deep does HydroCell™ technology hydrate?
HydroCell™ technology hydrates up to 10 layers deep within the stratum corneum – the skin’s outermost protective layer.¹
What are ceramides and why do they matter?
Ceramides are lipids that sit between skin cells in the stratum corneum, acting like mortar between bricks. They help prevent moisture loss and protect against external stressors. When levels fall, the skin barrier weakens. E45 HydroCell™ technology boosts ceramide synthesis by up to 51% in the stratum corneum and up to 56% in the upper epidermis.²
Which E45 HydroCell™ technology product is right for me?
All three share HydroCell™ technology as their core technology. HydroCell™ Smooth, with BHA and PHA, suits rough or uneven texture. HydroCell™ Glow, with Vitamin C and Niacinamide, is for dull or uneven-toned skin. HydroCell™ Firm, with Multi-Peptides, is designed for skin needing firming and improved elasticity.
- Within stratum corneum.
- Ex vivo test on HydroCell™ ingredient technology.
- In vivo test on HydroCell™ ingredient technology.









